UNVEILING THE MYSTERIES OF EPIGENETIC REGULATION
Here in Fondufe-Mittendorf lab, we study epigenetics and look great doing it! With outfits like this, it's impossible not to have fun in our lab, and we see no reason not to celebrate it!
NIEHS Keystone Science Lecture Series
In an NIEHS Keystone Science Lecture Series, Yvonne Fondufe-Mittendorf gave a talk about her research and the potential it has to help us understand possible causes of cancer development.
Congratulations to Rebekah Eleazer!
Congratulations to Rebekah Eleazer for being awarded an NSF fellowship! This award is highly competitive, and we are proud to have Rebekah in our lab!
Welcome to the Fondufe-Mittendorf lab. Our lab focuses on mechanisms by which chromatin and the epigenome are modulated during normal growth and in response to environmental cues. Our lab uses multifaceted approaches at the interface between biology, toxicology, bioinformatics and medicine, to study how when the modulation of chromatin and epigenomics goes awry, changes in gene expression ensues that then drive disease pathology. Our findings will not only provide a basic mechanistic insight into principles that govern gene regulation but will also inform on gene expression dysregulation in disease pathology and ultimately drug discovery.
To read more of Yvonne's publications, follow this link to PubMed!
I am investigating how dysregulation of histone variants drive nucleosome dynamics in carcinogenesis
I investigate how paternal exposure to cadmium modulates sperm DNA methylation.
PARP1-chromatin associations regulate RNA Pol II elongation to drive alternative splicing.
My project involves understanding the epigenetic regulator Methyl CpG-binding Protein 2.
My research is on regulation of chromatin structure and dynamics to drive gene expression.
My research seeks to understand epigenetic changes during carcinogenesis.
I am investigating the cicrRNA biogenesis and their function in arsenic-carcinogenesis.
Thanks to the high-schoolers, undergrads who made summer 2019 fun.
For any inquiries, questions or commendations, please call: 859-323-0091 or fill out the following form.
741 S. Limestone
Lexington, KY 40536
We are recruiting students and postdoctoral fellows with backgrounds and interests in all areas of biology including RNA biology, chromatin biology, genetics, computational biology/bioinformatics, and biophysics. Please send an email to